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Differential Gene Transcription in Honeybee (Apis cerana) Larvae Challenged by Chinese Sacbrood Virus (CSBV)
- Source :
- Sociobiology, Vol 60, Iss 4, Pp 413-420 (2014)
- Publication Year :
- 2014
- Publisher :
- Universidade Estadual de Feira de Santana, 2014.
-
Abstract
- Honey bees are economically important social insect. They are suffering from all kinds of pathogens, especially the virus. In response to pathogens, different immune pathways such as Toll, Imd, Jak-Stat and RNAi are involved. In the present study, the transcription analysis of 32 immune-related genes from Apis cerana challenged by Chinese sacbrood virus (CSBV), the most widely distributed virus in A. cerana, was carried out by qRT-PCR to provide cues for the antiviral mechanism and the effective control of bee viruses. The expression level of 22 genes were statistically changed, including 11 up-regulated genes (catus-2, lys-2, vir, s3a, mta1, faa, vhdl, co-1-iv, ago-1, ago-3, aub) in which 3 (ago-1, ago-3, aub) were related to RNAi pathway, and 11 down-regulated genes (kenny, pgrp-lc, pgrp-s2, abaecin, lys-1, lys-3, domeless, tepa, mlc, dscam, rpl8) related to Toll, Imd, and Jak-Stat pathways. The results indicated CSBV infection in A. cerana may activate a RNA-based antiviral immunity system. This work constituted the first report, under laboratory conditions, about induction of immune related genes in response to CSBV.
Details
- Language :
- English
- ISSN :
- 03616525
- Volume :
- 60
- Issue :
- 4
- Database :
- Directory of Open Access Journals
- Journal :
- Sociobiology
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.2618218dc79c4824a7e1d7f90699e3c4
- Document Type :
- article
- Full Text :
- https://doi.org/10.13102/sociobiology.v60i4.413-420