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Acute Myeloid Leukemia in Older Patients: From New Biological Insights to Targeted Therapies
- Source :
- Current Oncology, Vol 31, Iss 11, Pp 6632-6658 (2024)
- Publication Year :
- 2024
- Publisher :
- MDPI AG, 2024.
-
Abstract
- Acute myeloid leukemia (AML) is a heterogeneous blood-related neoplasm that predominantly afflicts older adults with a poor prognosis due to their physical condition and the presence of medical accompanying comorbidities, adverse biological disease features, and suitability for induction intensive chemotherapy and allogenic stem cells transplantation. Recent research into the molecular and biological factors contributing to disease development and progression has led to significant advancements in treatment approaches for older patients with AML. This review article discusses the latest biological and therapeutic developments that are transforming the management of AML in older adults.
Details
- Language :
- English
- ISSN :
- 17187729 and 11980052
- Volume :
- 31
- Issue :
- 11
- Database :
- Directory of Open Access Journals
- Journal :
- Current Oncology
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.258041d01a624da3b0a4ff2280cfb46c
- Document Type :
- article
- Full Text :
- https://doi.org/10.3390/curroncol31110490