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Signal processing and generation of bioactive nitric oxide in a model prototissue

Authors :
Songyang Liu
Yanwen Zhang
Xiaoxiao He
Mei Li
Jin Huang
Xiaohai Yang
Kemin Wang
Stephen Mann
Jianbo Liu
Source :
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

A challenge for synthetic biology is the design and construction of prototissue. Here, the authors spatially segregate layers of enzyme-decorated coacervate protocells as a model prototissue capable of chemical signal processing and modulating outputs of nitric oxide to inhibit blood clot formation.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
13
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.2552902d4d43422bbe7cceee7b124c19
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-022-32941-6