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Association between intracellular adenosine triphosphate content of CD4+ T lymphocytes and mortality in sepsis patients: A prospective observational study

Authors :
Ying Xian
Dan Xie
Jian Zhu
Changlong Zheng
Min Fan
Kefeng Jiang
Kouxing Zhang
Source :
Immunity, Inflammation and Disease, Vol 12, Iss 6, Pp n/a-n/a (2024)
Publication Year :
2024
Publisher :
Wiley, 2024.

Abstract

Abstract Objective This study aimed to link intracellular adenosine triphosphate content in CD4+ T lymphocytes (CD4+ iATP) with sepsis patient mortality, seeking a new predictive biomarker for outcomes and enhanced management. Methods 61 sepsis patients admitted to the Intensive Care Unit between October 2021 and November 2022 were enrolled. iATP levels were gauged using whole blood CD4+ T cells stimulated with mitogen PHA‐L. Based on CD4+ iATP levels (

Details

Language :
English
ISSN :
20504527
Volume :
12
Issue :
6
Database :
Directory of Open Access Journals
Journal :
Immunity, Inflammation and Disease
Publication Type :
Academic Journal
Accession number :
edsdoj.2547910cad62444f9a821f7ccdf493f1
Document Type :
article
Full Text :
https://doi.org/10.1002/iid3.1286