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Thermally damaged porcine skin is not a surrogate mechanical model of human skin

Authors :
Samara Gallagher
Uwe Kruger
Kartik Josyula
Rahul
Alex Gong
Agnes Song
Robert Sweet
Basiel Makled
Conner Parsey
Jack Norfleet
Suvranu De
Source :
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

Abstract Porcine skin is considered a de facto surrogate for human skin. However, this study shows that the mechanical characteristics of full thickness burned human skin are different from those of porcine skin. The study relies on five mechanical properties obtained from uniaxial tensile tests at loading rates relevant to surgery: two parameters of the Veronda-Westmann hyperelastic material model, ultimate tensile stress, ultimate tensile strain, and toughness of the skin samples. Univariate statistical analyses show that human and porcine skin properties are dissimilar (p

Subjects

Subjects :
Medicine
Science

Details

Language :
English
ISSN :
20452322
Volume :
12
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Scientific Reports
Publication Type :
Academic Journal
Accession number :
edsdoj.24edb487c49a42619a2c08bf5872646f
Document Type :
article
Full Text :
https://doi.org/10.1038/s41598-022-08551-z