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Juvenile Idiopathic Inflammatory Myopathy at a developing Paediatric Rheumatology Clinic in Trinidad and Tobago: a case series
- Source :
- Caribbean Medical Journal (2023)
- Publication Year :
- 2023
- Publisher :
- Trinidad and Tobago Medical Association (T&TMA), 2023.
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Abstract
- Objective: Juvenile Idiopathic Inflammatory Myopathy (JIIM) is a rare autoimmune disorder with no published data from the English-speaking Caribbean. As such, we seek to produce the first dataset from Trinidad and Tobago on this condition. Methods: Clinical notes of patients with JIIM, who attended the recently formed Paediatric Rheumatology Multi-Disciplinary Clinic over a 6-month period at the San Fernando Teaching Hospital were analysed. Clinically inactive disease at last visit was also assessed from the patients’ notes. Results: 5 patients clinical records were reviewed in this period. 4 were female and average age of onset was 6.8 years. 4 cases were Juvenile Dermatomyositis (JDM). The most common presenting complaints were skin rash and weakness whilst the most common additional symptoms were joint pains and pruritis. 2 patients had previous upper respiratory tract infection. Creatine Kinase was extremely elevated in one patient with juvenile polymyositis. 3 were positive for Antinuclear Antibodies. 2 patients were positive for Extractable Nuclear Antigen antibody (RP155). 3 patients utilized MRI which detected myositis in all reports. Oral medications included methotrexate and prednisolone. Parenteral drugs used included intravenous immunoglobulin and methylprednisolone. 4 patients had vitamin D supplementation and all 5 were prescribed physiotherapy. 2 had clinically inactive disease at last visit. Conclusions: This represents the first case series of JIIM in the English-Speaking Caribbean. Recommendations from this study include greater utilization of MRI in diagnostic workup and further evaluating anti RP155 antibody as a possible myositis associated antibody.
- Subjects :
- juvenile
idiopathic
inflammatory
myopathy
Medicine
Subjects
Details
- Language :
- English
- ISSN :
- 26645599
- Database :
- Directory of Open Access Journals
- Journal :
- Caribbean Medical Journal
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.24e3e907bdea468aaa5227f4caf55472
- Document Type :
- article