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Enhancing ketamine anesthesia with midazolam and fentanyl for children’s ear surgery: a prospective randomized study
- Source :
- Journal of Yeungnam Medical Science, Vol 41, Iss 3, Pp 207-212 (2024)
- Publication Year :
- 2024
- Publisher :
- Yeungnam University College of Medicine, Yeungnam University Institute Medical Science, 2024.
-
Abstract
- Background Myringotomy with tympanostomy tube insertion (MTI) is a superficial surgical procedure used to prevent hearing loss in children with serous otitis media. Intravenous anesthesia, often ketamine, is preferred for this procedure because of its ability to induce sedation without compromising airway reflexes. However, ketamine alone may be insufficient and potentially lead to spontaneous movement during surgery. This study evaluated the effectiveness of midazolam and fentanyl as adjuvants to ketamine in reducing spontaneous movement during MTI and enhancing the quality of recovery. Methods This study involved two groups of 30 patients each: one group received intravenous ketamine (1.5 mg/kg) with an equal volume of normal saline (K group), while the other received a combination of midazolam, fentanyl, and ketamine (0.05 mg/kg, 1 μg/kg, and 1.5 mg/kg, respectively; MFK group). We assessed side effects, intraoperative patient movement, surgeon satisfaction, and emergence agitation scores. Results The MFK group exhibited significantly lower scores for patient movement (p
- Subjects :
- fentanyl
ketamine
midazolam
otitis media
pediatric anesthesia
Medicine
Subjects
Details
- Language :
- English
- ISSN :
- 27998010
- Volume :
- 41
- Issue :
- 3
- Database :
- Directory of Open Access Journals
- Journal :
- Journal of Yeungnam Medical Science
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.245427edbce348fdae6d56e807541ef0
- Document Type :
- article
- Full Text :
- https://doi.org/10.12701/jyms.2024.00276