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The force of the myosin motor sets cooperativity in thin filament activation of skeletal muscles

Authors :
Marco Caremani
Matteo Marcello
Ilaria Morotti
Irene Pertici
Caterina Squarci
Massimo Reconditi
Pasquale Bianco
Gabriella Piazzesi
Vincenzo Lombardi
Marco Linari
Source :
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

Sarcomeres of Ca2 + -activated demembranated fibres of rabbit soleus muscles show that the stress exerted by each motor protein on the thin filament determines the cooperativity in thin filament activation.

Subjects

Subjects :
Biology (General)
QH301-705.5

Details

Language :
English
ISSN :
23993642
Volume :
5
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Communications Biology
Publication Type :
Academic Journal
Accession number :
edsdoj.23fb78ecf288475aa124accb1ee5533f
Document Type :
article
Full Text :
https://doi.org/10.1038/s42003-022-04184-0