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The gut microbiome is required for full protection against acute arsenic toxicity in mouse models

Authors :
Michael Coryell
Mark McAlpine
Nicholas V. Pinkham
Timothy R. McDermott
Seth T. Walk
Source :
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Publication Year :
2018
Publisher :
Nature Portfolio, 2018.

Abstract

It is unclear whether the gut microbiome can mitigate or exacerbate arsenic toxicity. Here, Coryell et al. show that the human gut microbiome protects mice from arsenic-induced mortality, with protection levels correlating with the relative abundance of the human commensal Faecalibacterium.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
9
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.2395c159cf4f4511ac552e2d6467ef5a
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-018-07803-9