Back to Search Start Over

Understanding the genetic determinants of the brain with MOSTest

Authors :
Dennis van der Meer
Oleksandr Frei
Tobias Kaufmann
Alexey A. Shadrin
Anna Devor
Olav B. Smeland
Wesley K. Thompson
Chun Chieh Fan
Dominic Holland
Lars T. Westlye
Ole A. Andreassen
Anders M. Dale
Source :
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Publication Year :
2020
Publisher :
Nature Portfolio, 2020.

Abstract

Regional brain morphology has a complex genetic architecture. Here the authors present MOSTest, a multivariate statistical framework, apply it to UK Biobank data, and discover hundreds of loci associated with regional brain morphology.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
11
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.23142a35894143158339487e31feb0c1
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-020-17368-1