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A scalable peptide-GPCR language for engineering multicellular communication

Authors :
Sonja Billerbeck
James Brisbois
Neta Agmon
Miguel Jimenez
Jasmine Temple
Michael Shen
Jef D. Boeke
Virginia W. Cornish
Source :
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Publication Year :
2018
Publisher :
Nature Portfolio, 2018.

Abstract

A bottleneck to engineered multicellular systems is the lack of a scalable signalling language. Here the authors use fungal mating peptide and GPCR pairs to build functional cell-to-cell communication links.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
9
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.2301b0715395466f978cf9be280cb30d
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-018-07610-2