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AQP4-AS1 Can Regulate the Expression of Ferroptosis-Related Regulator ALOX15 through Competitive Binding with miR-4476 in Lung Adenocarcinoma

Authors :
Lin Du
Geng Xu
Xiuqiang Zhang
Zhiwei Zhang
Yang Yang
Hongsheng Teng
Tao Yang
Source :
Global Medical Genetics, Vol 11, Iss 04, Pp 241-250 (2024)
Publication Year :
2024
Publisher :
Georg Thieme Verlag KG, 2024.

Abstract

Background The AQP4-AS1/miR-4476-ALOX15 regulatory axis was discovered in previous studies. We aimed to investigate the regulatory mechanism of the ferroptosis-related regulator ALOX15 by AQP4-AS1 and miR-4476 in lung adenocarcinoma (LUAD) and find new targets for clinical treatment.

Details

Language :
English
ISSN :
26999404
Volume :
11
Issue :
04
Database :
Directory of Open Access Journals
Journal :
Global Medical Genetics
Publication Type :
Academic Journal
Accession number :
edsdoj.22c549b350b74b839432a5e685bd74bf
Document Type :
article
Full Text :
https://doi.org/10.1055/s-0044-1789199