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AMPA Receptor Auxiliary Proteins of the CKAMP Family
- Source :
- International Journal of Molecular Sciences, Vol 20, Iss 6, p 1460 (2019)
- Publication Year :
- 2019
- Publisher :
- MDPI AG, 2019.
-
Abstract
- α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors are assembled of four core subunits and several additional interacting proteins. Cystine-knot AMPA receptor-modulating proteins (CKAMPs) constitute a family of four proteins that influence the trafficking, subcellular localization and function of AMPA receptors. The four CKAMP family members CKAMP39/shisa8, CKAMP44/shisa9, CKAMP52/shisa6 and CKAMP59/shisa7 differ in their expression profile and their modulatory influence on AMPA receptor function. In this review, I report about recent findings on the differential roles of CKAMP family members.
Details
- Language :
- English
- ISSN :
- 14220067
- Volume :
- 20
- Issue :
- 6
- Database :
- Directory of Open Access Journals
- Journal :
- International Journal of Molecular Sciences
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.227be3aa1ef64e8ab2ac48d4fa30e138
- Document Type :
- article
- Full Text :
- https://doi.org/10.3390/ijms20061460