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Malignancies in HIV/AIDS patients attending an outpatient clinic in Vitória, State of Espírito Santo, Brazil

Authors :
Lauro Ferreira da Silva Pinto Neto
Maria da Conceição Milanez
Jonathan Eric Golub
Angelica Espinosa Barbosa Miranda
Source :
Revista da Sociedade Brasileira de Medicina Tropical, Vol 45, Iss 6, Pp 687-690 (2012)
Publication Year :
2012
Publisher :
Sociedade Brasileira de Medicina Tropical (SBMT), 2012.

Abstract

INTRODUCTION: The present study investigated cancer prevalence and associated factors among HIV-infected individuals attending an AIDS outpatient clinic in Vitória, State of Espírito Santo, Brazil. METHODS: A sectional study was conducted among HIV infected adults attending an AIDS outpatient clinic in Vitória, State of Espírito Santo, Brazil. Demographic, epidemiological and clinical data were abstracted from medical records, including cancer diagnoses; nadir and current CD4 cell count, HIV viral load, time on antiretroviral treatment (ART), type of ART and smoking status. RESULTS: A total of 730 (91.3%) patients were included in the study. Median age was 44.0 [interquartile range (IQR): 35-50.3] years; median time since HIV diagnosis was 5.5 years (IQR: 2-10); 60% were male; and 59% were white. Thirty (4.1%) cases of cancer were identified of which 16 (53%) were AIDS defining cancers and 14 (47%) were non-AIDS defining malignancies. Patients diagnosed with cancer presented higher chance of being tobacco users [OR 2.2 (95% CI: 1.04-6.24)]; having nadir CD4 ≤200 cells/mm³ [OR 3.0 (95% CI: 1.19-7.81)] and higher lethality [OR 13,3 (95% CI: 4,57-38,72)]. CONCLUSIONS: These results corroborate the importance of screening for and prevention of non-AIDS defining cancers focus in HIV-infected population, as these cancers presented with similar frequency as AIDS defining cancers.

Details

Language :
English
ISSN :
16789849 and 00378682
Volume :
45
Issue :
6
Database :
Directory of Open Access Journals
Journal :
Revista da Sociedade Brasileira de Medicina Tropical
Publication Type :
Academic Journal
Accession number :
edsdoj.22610ac3a78842de9c7572318b105df1
Document Type :
article
Full Text :
https://doi.org/10.1590/S0037-86822012000600006