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Aion is a bistable anion-conducting channelrhodopsin that provides temporally extended and reversible neuronal silencing

Authors :
Silvia Rodriguez-Rozada
Jonas Wietek
Federico Tenedini
Kathrin Sauter
Neena Dhiman
Peter Hegemann
Peter Soba
J. Simon Wiegert
Source :
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

Aion is an anion-conducting, bistable channelrhodopsin that enables long-term silencing of neuronal networks, as demonstrated in organotypic hippocampal cultures and Drosophila melanogaster larvae.

Subjects

Subjects :
Biology (General)
QH301-705.5

Details

Language :
English
ISSN :
23993642
Volume :
5
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Communications Biology
Publication Type :
Academic Journal
Accession number :
edsdoj.22517d16d1e5465185854dba3c42e5e3
Document Type :
article
Full Text :
https://doi.org/10.1038/s42003-022-03636-x