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Inspection of Histological 3D Reconstructions in Virtual Reality

Authors :
Oleg Lobachev
Moritz Berthold
Henriette Pfeffer
Michael Guthe
Birte S. Steiniger
Source :
Frontiers in Virtual Reality, Vol 2 (2021)
Publication Year :
2021
Publisher :
Frontiers Media S.A., 2021.

Abstract

3D reconstruction is a challenging current topic in medical research. We perform 3D reconstructions from serial sections stained by immunohistological methods. This paper presents an immersive visualization solution to quality control (QC), inspect, and analyze such reconstructions. QC is essential to establish correct digital processing methodologies. Visual analytics, such as annotation placement, mesh painting, and classification utility, facilitates medical research insights. We propose a visualization in virtual reality (VR) for these purposes. In this manner, we advance the microanatomical research of human bone marrow and spleen. Both 3D reconstructions and original data are available in VR. Data inspection is streamlined by subtle implementation details and general immersion in VR.

Details

Language :
English
ISSN :
26734192
Volume :
2
Database :
Directory of Open Access Journals
Journal :
Frontiers in Virtual Reality
Publication Type :
Academic Journal
Accession number :
edsdoj.21f7f09e46274d8abaaea32b07707bf3
Document Type :
article
Full Text :
https://doi.org/10.3389/frvir.2021.628449