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Efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 lineages circulating in Brazil

Authors :
Sue Ann Costa Clemens
Pedro M. Folegatti
Katherine R. W. Emary
Lily Yin Weckx
Jeremy Ratcliff
Sagida Bibi
Ana Verena De Almeida Mendes
Eveline Pipolo Milan
Ana Pittella
Alexandre V. Schwarzbold
Eduardo Sprinz
Parvinder K. Aley
David Bonsall
Christophe Fraser
Michelle Fuskova
Sarah C. Gilbert
Daniel Jenkin
Sarah Kelly
Simon Kerridge
Teresa Lambe
Natalie G. Marchevsky
Yama F. Mujadidi
Emma Plested
Maheshi N. Ramasamy
Peter Simmonds
Tanya Golubchik
Merryn Voysey
Andrew J. Pollard
the AMPHEUS Project
Oxford COVID Vaccine Trial Team
Source :
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Publication Year :
2021
Publisher :
Nature Portfolio, 2021.

Abstract

Emerging variants of SARS-CoV-2 raise concerns about vaccine efficiency. Here, the authors present a post-hoc analysis for the ChAdOx1 nCoV-19 (AZD1222) vaccine trial in Brazil and provide efficacy against symptomatic COVID-19 caused by the Zeta (P.2) and other variants.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
12
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.2174b542d59f4531bfbfd908fa719572
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-021-25982-w