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Structural analysis of the SRP Alu domain from Plasmodium falciparum reveals a non-canonical open conformation

Authors :
Komal Soni
Georg Kempf
Karen Manalastas-Cantos
Astrid Hendricks
Dirk Flemming
Julien Guizetti
Bernd Simon
Friedrich Frischknecht
Dmitri I. Svergun
Klemens Wild
Irmgard Sinning
Source :
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Publication Year :
2021
Publisher :
Nature Portfolio, 2021.

Abstract

The SRP Alu domain is involved in co-translational protein targeting. Soni et al. investigate the Alu domain of Plasmodium falciparum, the agent of malaria, and find that unlike any other it adopts an open conformation.

Subjects

Subjects :
Biology (General)
QH301-705.5

Details

Language :
English
ISSN :
23993642
Volume :
4
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Communications Biology
Publication Type :
Academic Journal
Accession number :
edsdoj.209bda6b89384eceb72f2290525335c3
Document Type :
article
Full Text :
https://doi.org/10.1038/s42003-021-02132-y