A New Method to get the LVEF Reference Values of the Healthy Adult Male by Heart Rate and Geographical Environment Factors

Summary: Background: Finding a new method to get the Chinese healthy adult male LVEF reference values with heart rate & geo graphical environment factors. It is more accurate and simpler while considering different areas and individual differences. Methods: Collecting 3502 cases from more than 44 cities healthy adult male LVEF reference values and heart rate reference values (X1) within 10 years published articles in CNKI. A correlation analysis and ridge regression were employed to extract dependent geographical environment factors and predict the reference values of LVEF. The Kriging interpolation of geostatistical analysis were developed to reveal the spatial distribution characteristics of the LVEF values. Results: It has a correlation between LVEF and heart rate (X1)& geographical environment factors. The ridge regression equation of LVEF reference values and geographical environment factors is formula(1). The equation of LVEF reference values with heart rate and geographical environment factors is formula(2). Conclusion: The Chinese healthy adult male LVEF distribution showed a downward trend from south to north. Some geographical environment factors have impact on LVEF reference values including latitude, annual precipitation amount and mean air temperature distribution. LVEF is negative correlation with heart rate. When geographical environment factors and individual's heart rate are known, the local and individual's LVEF reference values can be derived from the formulas. Keywords: LVEF, reference values, heart rate, regional differences, geographical environment factors