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Genome-wide CRISPR screen identifies host dependency factors for influenza A virus infection
- Source :
- Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
- Publication Year :
- 2020
- Publisher :
- Nature Portfolio, 2020.
-
Abstract
- Here, Li et al. perform a genome-wide CRISPR screen to identify host dependency factors for influenza A virus infection and show that the host mRNA cap methyltransferase CMTR1 is important for viral cap snatching and that it affects expression of antiviral genes.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Volume :
- 11
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.1f734a4d6574c6d950eb373c2f18352
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s41467-019-13965-x