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Dengue virus co-opts innate type 2 pathways to escape early control of viral replication

Authors :
Chathuranga L. Fonseka
Clare S. Hardman
Jeongmin. Woo
Randeep Singh
Janina Nahler
Jiahe Yang
Yi-Ling Chen
Achala Kamaladasa
Tehani Silva
Maryam Salimi
Nicki Gray
Tao Dong
Gathsaurie N. Malavige
Graham S. Ogg
Source :
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

Group 2 innate lymphoid cells are activated during acute dengue viral infection in human, downregulate type I-IFN responsive gene and protein expression through Prostaglandin D2, and are permissive for productive dengue viral infection.

Subjects

Subjects :
Biology (General)
QH301-705.5

Details

Language :
English
ISSN :
23993642
Volume :
5
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Communications Biology
Publication Type :
Academic Journal
Accession number :
edsdoj.1f029b0885fe424d822999d259a66359
Document Type :
article
Full Text :
https://doi.org/10.1038/s42003-022-03682-5