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Evaluation of optimal medical therapy in acute myocardial infarction patients with prior stroke
- Source :
- Therapeutic Advances in Chronic Disease, Vol 12 (2021)
- Publication Year :
- 2021
- Publisher :
- SAGE Publishing, 2021.
-
Abstract
- Background: Treatment of acute myocardial infarction (AMI) patients with prior stroke is a common clinical dilemma. Currently, the application of optimal medical therapy (OMT) and its impact on clinical outcomes are not clear in this patient population. Methods: We retrieved 765 AMI patients with prior stroke who underwent percutaneous coronary intervention (PCI) during the index hospitalization from the international multicenter BleeMACS registry. All of the subjects were divided into two groups based on the prescription they were given prior to discharge. Baseline characteristics and procedural variables were compared between the OMT and non-OMT groups. Mortality, re-AMI, major adverse cardiovascular events (MACE), and bleeding were followed-up for 1 year. Results: Approximately 5% of all patients presenting with AMI were admitted to the hospital for ischemic stroke. Although the prescription rate of each OMT medication was reasonably high (73.3%–97.3%), 47.7% lacked at least one OMT medication. Patients receiving OMT showed a significantly decreased occurrence of mortality (4.5% vs 15.1%, p
- Subjects :
- Therapeutics. Pharmacology
RM1-950
Subjects
Details
- Language :
- English
- ISSN :
- 20406231 and 20406223
- Volume :
- 12
- Database :
- Directory of Open Access Journals
- Journal :
- Therapeutic Advances in Chronic Disease
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.1ed66cc14044431b9d2c3eb3e54f796c
- Document Type :
- article
- Full Text :
- https://doi.org/10.1177/20406223211046999