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Functionally Designed Nanovaccines against SARS-CoV-2 and Its Variants

Authors :
Yue Xi
Rongrong Ma
Shuo Li
Gang Liu
Chao Liu
Source :
Vaccines, Vol 12, Iss 7, p 764 (2024)
Publication Year :
2024
Publisher :
MDPI AG, 2024.

Abstract

COVID-19, generated by SARS-CoV-2, has significantly affected healthcare systems worldwide. The epidemic has highlighted the urgent need for vaccine development. Besides the conventional vaccination models, which include live-attenuated, recombinant protein, and inactivated vaccines, nanovaccines present a distinct opportunity to progress vaccine research and offer convenient alternatives. This review highlights the many widely used nanoparticle vaccine vectors, outlines their benefits and drawbacks, and examines recent developments in nanoparticle vaccines to prevent SARS-CoV-2. It also offers a thorough overview of the many advantages of nanoparticle vaccines, including an enhanced host immune response, multivalent antigen delivery, and efficient drug delivery. The main objective is to provide a reference for the development of innovative antiviral vaccines.

Details

Language :
English
ISSN :
2076393X
Volume :
12
Issue :
7
Database :
Directory of Open Access Journals
Journal :
Vaccines
Publication Type :
Academic Journal
Accession number :
edsdoj.1e9c6ce746324e6eb2760596e6e9eef6
Document Type :
article
Full Text :
https://doi.org/10.3390/vaccines12070764