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Nanomechanical DNA resonators for sensing and structural analysis of DNA-ligand complexes

Authors :
Stefano Stassi
Monica Marini
Marco Allione
Sergei Lopatin
Domenico Marson
Erik Laurini
Sabrina Pricl
Candido Fabrizio Pirri
Carlo Ricciardi
Enzo Di Fabrizio
Source :
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Publication Year :
2019
Publisher :
Nature Portfolio, 2019.

Abstract

Intercalating molecules can significantly change the conformation of DNA. Here, the authors fabricated resonators fully composed of DNA forming bundles between microfabricated pillars to study the vibration property of the DNA bundles with/without intercalant molecules.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
10
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.1df5a0fd518d4a9b9c962d7616f37f53
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-019-09612-0