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Determination of nevirapine in the presence of cucurbit(7)uril with a gold electrode

Authors :
Ana E. Esteva
Elías Blanco
Juan J. Piña
Abel I. Balbin
Carmen Quintana
Pedro Hernández
Source :
Journal of Electrochemical Science and Engineering, Vol 4, Iss 1 (2014)
Publication Year :
2014
Publisher :
International Association of Physical Chemists (IAPC), 2014.

Abstract

The electrochemical oxidation of nevirapine, an anti-HIV drug, at a gold electrode was studied by voltammetric techniques. Nevirapine showed a signal that interfered with a working electrode wave. This interference was solved by the use of cucurbit(7)uril allowing nevirapine to be determined in tablets (80.4 % recovery, presence of stavudine and lamivudine) and urine (98.4 %).

Subjects

Subjects :
Chemistry
QD1-999

Details

Language :
English
ISSN :
18479286
Volume :
4
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Journal of Electrochemical Science and Engineering
Publication Type :
Academic Journal
Accession number :
edsdoj.1d92fde45650480e980f519f61f68ca6
Document Type :
article
Full Text :
https://doi.org/10.5599/111