Ultrasound Speckle Decorrelation Analysis‐Based Velocimetry for 3D‐Velocity‐Components Measurement Using a 1D Transducer Array

Abstract Ultrasound velocimetry has been widely used for blood flow imaging. However, the flow measurements are constrained to resolve the in‐plane 2D flow components when using a 1D transducer array. In this work, an ultrasound speckle decorrelation analysis‐based velocimetry (3C‐vUS) is proposed for 3D velocity components measurement using a 1D transducer array. The 3C‐vUS theory is first derived and validated with numerical simulations and phantom experiments. The in vivo testing results show that 3C‐vUS can accurately measure the blood flow 3D‐velocity‐components of the human carotid artery at arbitrary probe‐to‐vessel angles throughout the cardiac cycle. With such capability, the 3C‐vUS will alleviate the requirement of operators and promote disease screening for blood flow‐related disorders.