Risk stratification for nasopharyngeal carcinoma: a real-world study based on locoregional extension patterns and Epstein-Barr virus DNA load

Authors :: Lu-Lu Zhang
Meng-Yao Huang
Fei-Xu
Ke-Xin Wang
Di Song
Ting Wang
Li-Yue Sun
Jian-Yong Shao
Source :: Therapeutic Advances in Medical Oncology, Vol 12 (2020)
Publication Year :: 2020
Publisher :: SAGE Publishing, 2020.
Abstract: Aim: The present study aimed to evaluate the combined value of locoregional extension patterns (LEPs) and circulating cell-free Epstein–Barr virus (cf EBV) DNA for risk stratification of locoregionally advanced nasopharyngeal carcinoma (LA-NPC) to better guide therapeutic strategies. Methods: A total of 7227 cases of LA-NPC were reviewed retrospectively and classified into six groups according to their LEP (ascending, descending, or mixed type) and pre-treatment cf EBV-DNA load (⩾ versus

Subjects :: Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282

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