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Postnatal corticosteroid use for prevention or treatment of bronchopulmonary dysplasia in England and Wales 2012–2019: a retrospective population cohort study

Authors :
Neena Modi
Chris Gale
Iyad Al-Muzaffar
Jonathan Cusack
Victoria Nesbitt
Sanjay Salgia
Matthew Babirecki
Aashish Gupta
L M Wong
Anita Mittal
Ahmed Hassan
Karin Schwarz
Graham Whincup
Abdul Hasib
Mehdi Garbash
David Gibson
Pauline Adiotomre
Abby Deketelaere
Stanley Zengeya
Cath Seagrave
Hilary Dixon
Narendra Aladangady
Hassan Gaili
Matthew James
M Lal
Lawrence Miall
Venkatesh Kairamkonda
J Kefas
Jennifer Birch
Gail Whitehead
I Misra
Subodh Gupta
Steven Wardle
Eleri Adams
Minesh Khashu
Charlotte Groves
Christos Zipitis
Peter De Halpert
Joanne Fedee
Stephen Jones
Kirsten Mack
Charlotte Huddy
Salim Yasin
Ngozi Edi-osagie
Carrie Heal
Jacqeline Birch
Hari Kumar
Chris Rawlingson
Delyth Webb
Sankara Narayanan
Elizabeth Eyre
Caroline Sullivan
Wynne Leith
Vimal Vasu
Katia Vamvakiti
Megan Eaton
Ambalika Das
Katharine Mcdevitt
Anna Gregory
Shu-Ling Chuang
Sabita Uthaya
Cheryl Battersby
Imran Ahmed
Chris Warren
Tristan Bate
Mark Johnson
Sunil Reddy
Rashmi Gandhi
Nitin Goel
Richard Hearn
Cheentan Singh
Faith Emery
Vineet Gupta
Yee Aung
Vennila Ponnusamy
Pinki Surana
Anand Kamalanathan
Kavi Aucharaz
Lindsay Halpern
Matt Nash
Alex Allwood
Nigel Brooke
Jennifer Holman
Geraint Lee
Sobia Balal
Poornima Pandey
Ravindra Bhat
Simon Rhodes
Savi Sivashankar
Michael Grosdenier
Ajay Reddy
Prakash Thiagarajan
Chinnappa Reddy
Lidia Tyszcuzk
Glynis Rewitzky
Bushra Abdul-Malik
Dominic Muogbo
Angela D'Amore
John McIntyre
Lucinda Winckworth
Jim Baird
Akinsola Ogundiya
Pamela Cairns
Porus Bastani
Marice Theron
Siba Paul
Giles Kendall
Puneet Nath
Ros Garr
Sundeep Sandhu
Michael Cronin
Alison Bedford Russell
Ruchika Gupta
Archana Mishra
Oluseun Tayo
Priya Muthukumar
Brendan Harrington
Victoria Sharp
Nicola Johnson
Sam Wallis
Prashanth Bhat
Lee Abbott
Raju Narasimhan
Kate Creese
Divyen Shah
Clare Cane
Ghada Ramadan
Sijia Yao
Alistair Ewing
Penelope Young
Ramona Onita
Joanne Dangerfield
Jocelyn Morris
Toria Klutse
Sonia Spathis
Sathish Krishnan
Samar Sen
Jez Jones
Geedi Farah
Prem Pitchaikani
Jonathan Filkin
Ashok Karupaiah
Richard Heaver
Mohammad Alam
Tiziana Fragapane
Jess Reynolds
Khadija Ben-Sasi
Patricia Cowley
Shilpa Ramesh
Julia Croft
Soma Sengupta
Nagendra Venkata
Anitha Vayalakkad
Ben Obi
Anjali Petkar
Arun Ramachandran
Se-Yeon Park
Sue Bird
Jageer Mohammed
Sanjay Jaisal
Source :
BMJ Open, Vol 12, Iss 11 (2022)
Publication Year :
2022
Publisher :
BMJ Publishing Group, 2022.

Abstract

Objective Describe the population of babies who do and do not receive postnatal corticosteroids for prevention or treatment of bronchopulmonary dysplasia (BPD).Design Retrospective cohort study using data held in the National Neonatal Research Database.Setting National Health Service neonatal units in England and Wales.Patients Babies born less than 32 weeks gestation and admitted to neonatal units from 1 January 2012 to 31 December 2019.Main outcomes Proportion of babies given postnatal corticosteroid; type of corticosteroid; age at initiation and duration, trends over time.Secondary outcomes Survival to discharge, treatment for retinopathy of prematurity, BPD, brain injury, severe necrotising enterocolitis, gastrointestinal perforation.Results 8% (4713/62019) of babies born

Subjects

Subjects :
Medicine

Details

Language :
English
ISSN :
20446055
Volume :
12
Issue :
11
Database :
Directory of Open Access Journals
Journal :
BMJ Open
Publication Type :
Academic Journal
Accession number :
edsdoj.1c9cf1736de4b08bb3863c44f9752bd
Document Type :
article
Full Text :
https://doi.org/10.1136/bmjopen-2022-063835