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Next generation plasma proteome profiling to monitor health and disease

Authors :
Wen Zhong
Fredrik Edfors
Anders Gummesson
Göran Bergström
Linn Fagerberg
Mathias Uhlén
Source :
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Publication Year :
2021
Publisher :
Nature Portfolio, 2021.

Abstract

The proximity extension assay (PEA) is a popular tool to measure plasma protein levels. Here, the authors extend the proteome coverage of PEA by combining it with next-generation sequencing, enabling the analysis of nearly 1500 proteins from minute amounts of plasma.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
12
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.1bbb3cacc2fd454eb90474d2d27c313f
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-021-22767-z