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DC3 is a method for deconvolution and coupled clustering from bulk and single-cell genomics data

Authors :
Wanwen Zeng
Xi Chen
Zhana Duren
Yong Wang
Rui Jiang
Wing Hung Wong
Source :
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Publication Year :
2019
Publisher :
Nature Portfolio, 2019.

Abstract

Single-cell omics analysis can reveal heterogeneity among individual cells at different levels. Here, the authors develop DC3, a computational method for joint analysis of various bulk and single-cell data from the same heterogeneous cell population.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
10
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.1b95ca72225a421798a545948feed603
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-019-12547-1