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Treg engage lymphotoxin beta receptor for afferent lymphatic transendothelial migration
- Source :
- Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
- Publication Year :
- 2016
- Publisher :
- Nature Portfolio, 2016.
-
Abstract
- Lymphotoxin regulates lymphoid organ architecture and adhesion molecules involved in lymphocyte trafficking. Here the authors show that lymphotoxin produced by regulatory T cells promotes their migration to the draining lymph nodes by engaging its cognate receptor on lymphatic endothelial cells.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Volume :
- 7
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.1b7c04c5e344820ad62ca3e16a0863c
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/ncomms12021