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Digestive perianastomotic ulcerations after intestinal resection in children

Authors :
Weicheng Zhang
Source :
World Journal of Pediatric Surgery, Vol 6, Iss 3 (2023)
Publication Year :
2023
Publisher :
BMJ Publishing Group, 2023.

Abstract

Digestive perianastomotic ulceration (DPAU) is a rare complication after intestinal resection and anastomosis occurring at or near the anastomosis site. The purpose of this review is to summarize the characteristics of DPAU, including the etiology, diagnosis and differential diagnosis, clinical manifestations, treatment, and future research. All recent literature on DPAU was searched in PubMed, Embase, and Cochrane and then reviewed. The clinical manifestations of DPAU are mainly gastrointestinal symptoms such as bloody stool and chronic anemia. The diagnosis of DPAU is difficult. Specific diseases, such as Crohn’s disease, must be ruled out before a diagnosis can be made. In addition, there are no clear treatment guidelines due to the high degree of heterogeneity in response to drugs and surgery. It is recommended to adjust medication in time and combine various treatment methods. In addition, the mechanism that causes DPAU is not well understood; however, several possible mechanisms have been proposed, such as scar tissue ischemia and underlying diseases. Moreover, there is a high risk of relapses, and a long-term follow-up is necessary. Numerous issues remain to be solved in this area; therefore, more randomized controlled trials and studies should be carried out to further understand this disease.

Subjects

Subjects :
Pediatrics
RJ1-570
Surgery
RD1-811

Details

Language :
English
ISSN :
25165410
Volume :
6
Issue :
3
Database :
Directory of Open Access Journals
Journal :
World Journal of Pediatric Surgery
Publication Type :
Academic Journal
Accession number :
edsdoj.1b4f0488c0244931a87a126c5e1f7a93
Document Type :
article
Full Text :
https://doi.org/10.1136/wjps-2022-000533