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Crystal structure and Hirshfeld surface analysis of 2-{[7-acetyl-4-cyano-6-hydroxy-8-(4-methoxyphenyl)-1,6-dimethyl-5,6,7,8-tetrahydroisoquinolin-3-yl]sulfanyl}acetic acid ethyl ester
- Source :
- Acta Crystallographica Section E: Crystallographic Communications, Vol 78, Iss 2, Pp 220-224 (2022)
- Publication Year :
- 2022
- Publisher :
- International Union of Crystallography, 2022.
-
Abstract
- In the title molecule, C25H28N2O5S, (alternative name ethyl 2-{[7-acetyl-4-cyano-6-hydroxy-8-(4-methoxyphenyl)-1,6-dimethyl-5,6,7,8-tetrahydroisoquinolin-3-yl]sulfanyl}acetate) the 4-methoxyphenyl group is disposed on one side of the bicyclic core and the oxygen atoms of the hydroxyl and acetyl groups are disposed on the other side. In the crystal, a layered structure parallel to the ac plane is generated by O—H...O and C—H...O hydrogen bonds plus C—H...π(ring) interactions.
Details
- Language :
- English
- ISSN :
- 20569890
- Volume :
- 78
- Issue :
- 2
- Database :
- Directory of Open Access Journals
- Journal :
- Acta Crystallographica Section E: Crystallographic Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.1b3135dd48184df2a685a5639e2b0ca3
- Document Type :
- article
- Full Text :
- https://doi.org/10.1107/S2056989022000378