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The Increased Expression of CCL20 and CCR6 in Rectal Mucosa Correlated to Severe Inflammation in Pediatric Ulcerative Colitis

Authors :
Keiichi Uchida
Yuhki Koike
Kiyoshi Hashimoto
Susumu Saigusa
Mikihiro Inoue
Kohei Otake
Koji Tanaka
Kohei Matsushita
Yoshiki Okita
Hiroyuki Fujikawa
Toshimitsu Araki
Yasuhiko Mohri
Masato Kusunoki
Source :
Gastroenterology Research and Practice, Vol 2015 (2015)
Publication Year :
2015
Publisher :
Hindawi Limited, 2015.

Abstract

Background/Aims. The aim of this study is to clarify the differences of CCL20 and CCR6 expression, chemokine correlated to intestinal homeostasis, between pediatric and adult ulcerative colitis (UC) patients. Methods. Onehundred forty-one patients who underwent proctocolectomy were divided to two groups including childhood-onset UC (CUC,

Details

Language :
English
ISSN :
16876121 and 1687630X
Volume :
2015
Database :
Directory of Open Access Journals
Journal :
Gastroenterology Research and Practice
Publication Type :
Academic Journal
Accession number :
edsdoj.1a8ecacbb6904095b1d7c84ee53c67af
Document Type :
article
Full Text :
https://doi.org/10.1155/2015/856532