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A dermocosmetic containing bakuchiol, Ginkgo biloba extract and mannitol improves the efficacy of adapalene in patients with acne vulgaris: result from a controlled randomized trial
- Source :
- Clinical, Cosmetic and Investigational Dermatology, Vol 2015, Iss default, Pp 187-191 (2015)
- Publication Year :
- 2015
- Publisher :
- Dove Medical Press, 2015.
-
Abstract
- Katarína Poláková,1 Aurélie Fauger,2 Michèle Sayag,2 Eric Jourdan2 1Saint Elisabeth´s Oncological Institute, Bratislava, Slovakia; 2Laboratoire Bioderma, Lyon, France Background: Acne vulgaris is an inflammatory disorder of the pilosebaceous unit. Aim: To confirm that BGM (bakuchiol, Ginkgo biloba extract, and mannitol) complex increases the established clinical efficacy of adapalene 0.1% gel in patients with acne. Methods: A clinical trial was conducted in acne patients. A total of 111 subjects received adapalene 0.1% gel and BGM complex or vehicle cream for 2 months. Assessments comprised Investigator Global Assessment (IGA), global efficacy, seborrhea intensity, inflammatory and non-inflammatory lesions, and subject perception, as well as overall safety and local tolerance and quality of life. Results: At the end of the trial, inflammatory and non-inflammatory lesions, IGA, global efficacy, and seborrhea intensity had significantly improved in both treatment groups. Differences were statistically significant (P
- Subjects :
- Dermatology
RL1-803
Subjects
Details
- Language :
- English
- ISSN :
- 11787015
- Volume :
- 2015
- Issue :
- default
- Database :
- Directory of Open Access Journals
- Journal :
- Clinical, Cosmetic and Investigational Dermatology
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.1a43323f7c6643908ee4c40d09bae06f
- Document Type :
- article