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A comparison of Selective Aortic Arch Perfusion and Resuscitative Endovascular Balloon Occlusion of the Aorta for the management of hemorrhage-induced traumatic cardiac arrest: A translational model in large swine.

Authors :
Ed B G Barnard
James E Manning
Jason E Smith
Jason M Rall
Jennifer M Cox
James D Ross
Source :
PLoS Medicine, Vol 14, Iss 7, p e1002349 (2017)
Publication Year :
2017
Publisher :
Public Library of Science (PLoS), 2017.

Abstract

Survival rates remain low after hemorrhage-induced traumatic cardiac arrest (TCA). Noncompressible torso hemorrhage (NCTH) is a major cause of potentially survivable trauma death. Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) at the thoracic aorta (Zone 1) can limit subdiaphragmatic blood loss and allow for IV fluid resuscitation when intrinsic cardiac activity is still present. Selective Aortic Arch Perfusion (SAAP) combines thoracic aortic balloon hemorrhage control with intra-aortic oxygenated perfusion to achieve return of spontaneous circulation (ROSC) when cardiac arrest has occurred.Male Yorkshire Landrace cross swine (80.0 ± 6.0 kg) underwent anesthesia, instrumentation for monitoring, and splenectomy. TCA was induced by laparoscopic liver lobe resection combined with arterial catheter blood withdrawal to achieve a sustained systolic blood pressure

Subjects

Subjects :
Medicine

Details

Language :
English
ISSN :
15491277 and 15491676
Volume :
14
Issue :
7
Database :
Directory of Open Access Journals
Journal :
PLoS Medicine
Publication Type :
Academic Journal
Accession number :
edsdoj.19f7bf16385f4634a9db5592638e1666
Document Type :
article
Full Text :
https://doi.org/10.1371/journal.pmed.1002349