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Evaluation of rK-39 strip test using urine for diagnosis of visceral leishmaniasis in an endemic area in Bangladesh
- Source :
- Parasites & Vectors, Vol 3, Iss 1, p 114 (2010)
- Publication Year :
- 2010
- Publisher :
- BMC, 2010.
-
Abstract
- Abstract Diagnosis of visceral leishmaniasis (VL) by demonstration of parasites in tissue smears obtained from bone marrow, spleen or lymph nodes is risky, painful, and difficult. The rK-39 strip test is widely used for the diagnosis of VL using blood/serum samples in endemic countries. The aim of the study was to evaluate the rK-39 strip test using urine sample as a non-invasive means for the diagnosis of VL. The rk-39 strip test was performed using urine from 100 suspected VL cases along with 25 disease control (malarial febrile cases) and 50 healthy control (from endemic and non-endemic areas). All the VL suspected cases were positive with the rK-39 strip test using serum. The sensitivity and specificity of the rK-39 strip test using urine samples was 95% and 93.3%, respectively, compared to serum based rK-39 test. The findings suggest that the urine based rK-39 test could be a practical and efficient tool for the diagnosis of VL patients in rural areas, particularly where resources are limited.
- Subjects :
- Infectious and parasitic diseases
RC109-216
Subjects
Details
- Language :
- English
- ISSN :
- 17563305
- Volume :
- 3
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Parasites & Vectors
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.19f37f59ffd249de8376def847b35fb7
- Document Type :
- article
- Full Text :
- https://doi.org/10.1186/1756-3305-3-114