Back to Search Start Over

Screening of nasopharyngeal cancer in high-risk familial cohort: A practical approach using a screening algorithm

Authors :
Jia Jia Wee
Isabelle Jia Hui Jang
Neville Wei Yang Teo
Ian Chi Yuan Loh
Tze Choong Charn
Donovan Kum Chuen Eu
Raymond King Yin Tsang
Ming Yann Lim
Lilleen Minyi Huang
Paul Kan Hwei Mok
Song Tar Toh
Chwee Ming Lim
Source :
Annals, Academy of Medicine, Singapore, Vol 53, Iss 4, Pp 268-271 (2024)
Publication Year :
2024
Publisher :
Academy of Medicine Singapore, 2024.

Abstract

In Singapore, nasopharyngeal cancer (NPC) is among the top 3 cancers afflicting middle-aged males (30–49 years old).1 Unfortunately, patients with early-stage NPC are often asymptomatic, and most patients (approx. 70%) are diagnosed with advanced disease with adversely reduced survival. First-degree relatives of NPC patients have about 4 to 10 times increased risk of developing NPC,2 and strategies for reducing NPC-specific mortality among this high-risk group are feasible. Herein, a working group from the Chapter Board of Otorhinolaryngologists Singapore proposed a screening algorithm for these high-risk individuals of NPC based on existing available evidence.

Subjects

Subjects :
Medicine

Details

Language :
English
ISSN :
29724066
Volume :
53
Issue :
4
Database :
Directory of Open Access Journals
Journal :
Annals, Academy of Medicine, Singapore
Publication Type :
Academic Journal
Accession number :
edsdoj.198dc427ac1b4a719eaad76124cb3539
Document Type :
article
Full Text :
https://doi.org/10.47102/annals-acadmedsg.2023273