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Human chronic chagasic cardiopathy: participation of parasite antigens, subsets of lymphocytes, cytokines and microvascular abnormalities
- Source :
- Memorias do Instituto Oswaldo Cruz, Vol 94, Pp 263-267 (1999)
- Publication Year :
- 1999
- Publisher :
- Fundação Oswaldo Cruz (FIOCRUZ), 1999.
-
Abstract
- This article tries to demonstrate by new pathological findings (with the use of immunohistochemical technique and confocal laser microscopy) that chronic chagasic cardiomyopathy is a result of multiple factors involving myocarditis, immunodepression, severe fibrosis and microvessels dilatation and that all of these alterations are probably directly related with the presence of Trypanosoma cruzi parasites in the host associated with inadequate immunological response of the host.
Details
- Language :
- English
- ISSN :
- 00740276 and 16788060
- Volume :
- 94
- Database :
- Directory of Open Access Journals
- Journal :
- Memorias do Instituto Oswaldo Cruz
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.195349c1b08b4aaeacb458cd74db2466
- Document Type :
- article
- Full Text :
- https://doi.org/10.1590/S0074-02761999000700044