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Patients With Lung Cancer Have High Susceptibility of COVID-19: A Retrospective Study in Wuhan, China

Authors :
Meng-Yuan Dai
Zhen Chen
Yan Leng
Meng Wu
Yu Liu
Fuxiang Zhou
Chen Ming
Ningyi Shao
Miao Liu
Hongbing Cai
Source :
Cancer Control, Vol 27 (2020)
Publication Year :
2020
Publisher :
SAGE Publishing, 2020.

Abstract

Patients with lung cancer are presumed to be at high risk from COVID-19 infection due to underlying malignancy. A total of 31 COVID-19 patients with pre-diagnosed lung cancer and 186 age and sex matched COVID-19 patients without cancer in 6 hospitals in Wuhan, China were identified in our study. There was a significantly higher level of IL-6 in lung cancer group showed by multifactorial analysis. The restricted mean survival time in 10, 20, and 53 days in COVID-19 patients with lung cancer were ealier than non-cancer COVID-19 patients in the same observation time (all P values < 0.05). Our results indicated that pre-diagnosed lung cancer was associated with higher morbidity and mortality in COVID-19 patients.

Details

Language :
English
ISSN :
10732748
Volume :
27
Database :
Directory of Open Access Journals
Journal :
Cancer Control
Publication Type :
Academic Journal
Accession number :
edsdoj.18f57c6daf824599b884d59b7f81e5a0
Document Type :
article
Full Text :
https://doi.org/10.1177/1073274820960467