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Comprehensive omic characterization of breast cancer in Mexican-Hispanic women

Authors :
Sandra L. Romero-Cordoba
Ivan Salido-Guadarrama
Rosa Rebollar-Vega
Veronica Bautista-Piña
Carlos Dominguez-Reyes
Alberto Tenorio-Torres
Felipe Villegas-Carlos
Juan C. Fernández-López
Laura Uribe-Figueroa
Luis Alfaro-Ruiz
Alfredo Hidalgo-Miranda
Source :
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Publication Year :
2021
Publisher :
Nature Portfolio, 2021.

Abstract

Cancers in different populations have been shown to be genetically distinct. Here, the authors sequence breast cancers from Mexican-Hispanic patients and find that these patients have a higher percentage of Akt1 mutations compared to Caucasian and Asian populations, suggesting these are clinically actionable.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
12
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.18d53057ea47c8996ebd5a4ca3bc1a
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-021-22478-5