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Retrospective analysis of pacritinib in patients with myelofibrosis and severe thrombocytopenia

Authors :
Srdan Verstovsek
Ruben Mesa
Moshe Talpaz
Jean-Jacques Kiladjian
Claire N. Harrison
Stephen T. Oh
Alessandro M. Vannucchi
Raajit Rampal
Bart L. Scott
Sarah A. Buckley
Adam R. Craig
Karisse Roman-Torres
John O. Mascarenhas
Source :
Haematologica, Vol 107, Iss 7 (2021)
Publication Year :
2021
Publisher :
Ferrata Storti Foundation, 2021.

Abstract

Thrombocytopenia is common in patients with myelofibrosis (MF) and is a well-established adverse prognostic factor. Both of the approved Janus kinase (JAK) inhibitors, ruxolitinib and fedratinib, can worsen thrombocytopenia and have not been evaluated in patients with severe thrombocytopenia (platelet counts

Details

Language :
English
ISSN :
03906078 and 15928721
Volume :
107
Issue :
7
Database :
Directory of Open Access Journals
Journal :
Haematologica
Publication Type :
Academic Journal
Accession number :
edsdoj.18d1fcd53bdb4ab4a00ad741474aea14
Document Type :
article
Full Text :
https://doi.org/10.3324/haematol.2021.279415