Back to Search
Start Over
Cytokine levels in pleural fluid as markers of acute rejection after lung transplantation
- Source :
- Jornal Brasileiro de Pneumologia, Vol 40, Iss 4, Pp 425-428 (2014)
- Publication Year :
- 2014
- Publisher :
- Sociedade Brasileira de Pneumologia e Tisiologia, 2014.
-
Abstract
- Our objective was to determine the levels of lactate dehydrogenase, IL-6, IL-8, and VEGF, as well as the total and differential cell counts, in the pleural fluid of lung transplant recipients, correlating those levels with the occurrence and severity of rejection. We analyzed pleural fluid samples collected from 18 patients at various time points (up to postoperative day 4). The levels of IL-6, IL-8, and VEGF tended to elevate in parallel with increases in the severity of rejection. Our results suggest that these levels are markers of acute graft rejection in lung transplant recipients.
Details
- Language :
- English, Portuguese
- ISSN :
- 18063756 and 18063713
- Volume :
- 40
- Issue :
- 4
- Database :
- Directory of Open Access Journals
- Journal :
- Jornal Brasileiro de Pneumologia
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.189bb52835384ed8934e923bc389ee09
- Document Type :
- article
- Full Text :
- https://doi.org/10.1590/S1806-37132014000400011