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Prognostic factors in the primary care of patients with Merkel cell carcinoma: A monocentric cohort study of 108 patients from a tertiary referral centre
- Source :
- JEADV Clinical Practice, Vol 2, Iss 4, Pp 810-818 (2023)
- Publication Year :
- 2023
- Publisher :
- Wiley, 2023.
-
Abstract
- Abstract Background Merkel cell carcinoma (MCC) is one of the deadliest skin cancers. Despite existing national guidelines, treatment of MCC patients is not as well standardized as for more common skin cancers. Objectives The study objective was to investigate factors predisposing to favourable/unfavourable patient outcomes and to which extent guideline‐based care affects patient survival. Methods This noninterventional study investigated a monocentre real‐world patient cohort with a histologically confirmed diagnosis of MCC who presented at the skin cancer centre, University Hospital Essen. Patient and tumour characteristics (age, sex, primary localization, Merkel cell polyomavirus [MCPyV], tumour stage at initial diagnosis and primary treatment measures [surgery, radiation]) were correlated with the patient outcome in terms of recurrence‐free survival (RFS) and overall survival (OS). Results A total of 108 patients were identified. The median age of the patients was 69.9 years (range 39–88), with patients aged
Details
- Language :
- English
- ISSN :
- 27686566
- Volume :
- 2
- Issue :
- 4
- Database :
- Directory of Open Access Journals
- Journal :
- JEADV Clinical Practice
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.188049c65be2447ba65d4615d59cda63
- Document Type :
- article
- Full Text :
- https://doi.org/10.1002/jvc2.231