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Lead Identification of 8‑(Methylamino)-2-oxo-1,2-dihydroquinoline Derivatives as DNA Gyrase Inhibitors: Hit-to-Lead Generation Involving Thermodynamic Evaluation

Authors :
Fumihito Ushiyama
Hideaki Amada
Tomoki Takeuchi
Nozomi Tanaka-Yamamoto
Harumi Kanazawa
Koichiro Nakano
Masashi Mima
Aiko Masuko
Iichiro Takata
Kosuke Hitaka
Kunihiko Iwamoto
Hiroyuki Sugiyama
Norikazu Ohtake
Source :
ACS Omega, Vol 5, Iss 17, Pp 10145-10159 (2020)
Publication Year :
2020
Publisher :
American Chemical Society, 2020.

Subjects

Subjects :
Chemistry
QD1-999

Details

Language :
English
ISSN :
24701343
Volume :
5
Issue :
17
Database :
Directory of Open Access Journals
Journal :
ACS Omega
Publication Type :
Academic Journal
Accession number :
edsdoj.17fa358e19ce435eaf8d3e740e6f6ab1
Document Type :
article
Full Text :
https://doi.org/10.1021/acsomega.0c00865