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Ferroptosis-related alternative splicing signatures as potential biomarkers for predicting prognosis and therapy response in gastric cancer
- Source :
- Heliyon, Vol 10, Iss 14, Pp e34381- (2024)
- Publication Year :
- 2024
- Publisher :
- Elsevier, 2024.
-
Abstract
- Ferroptosis is linked to various tumor biological traits, and alternative splicing (AS), a crucial step in mRNA processing, plays a role in the post-transcriptional regulation of ferroptosis-related genes (FRGs). A least absolute shrinkage and selection operator (LASSO) penalized Cox regression analysis was utilized to build a prognostic signature based on 12 AS events (p 0.4, FDR
Details
- Language :
- English
- ISSN :
- 24058440
- Volume :
- 10
- Issue :
- 14
- Database :
- Directory of Open Access Journals
- Journal :
- Heliyon
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.16a7d8d00b3248e9be3e8b19ad1f62c5
- Document Type :
- article
- Full Text :
- https://doi.org/10.1016/j.heliyon.2024.e34381