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Exploring the immunomodulatory role of depot medroxyprogesterones acetate and endogenous progesterone levels in HIV infected and uninfected women

Authors :
Nonzwakazi Mnqonywa
Nathlee Abbai
Viswanath Ragupathy
Gita Ramjee
Indira Hewlett
Dhayendre Moodley
Source :
BMC Research Notes, Vol 12, Iss 1, Pp 1-5 (2019)
Publication Year :
2019
Publisher :
BMC, 2019.

Abstract

Abstract Objective The aim of this proof of concept study was to determine the effect of depot medroxyprogesterone acetate on host and viral factors in HIV infected and uninfected women. Results In this study, the gene expression levels for CCL5, CCR5 and CXCR4 was significantly higher in HIV positive women when compared to HIV negative women (p

Details

Language :
English
ISSN :
17560500
Volume :
12
Issue :
1
Database :
Directory of Open Access Journals
Journal :
BMC Research Notes
Publication Type :
Academic Journal
Accession number :
edsdoj.16545a5c30b947a2bd505f8c74760a2f
Document Type :
article
Full Text :
https://doi.org/10.1186/s13104-019-4785-z