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Analysis of the Evolution of Pandemic Influenza A(H1N1) Virus Neuraminidase Reveals Entanglement of Different Phenotypic Characteristics

Authors :
Meiling Dai
Wenjuan Du
Carles Martínez-Romero
Tim Leenders
Tom Wennekes
Guus F. Rimmelzwaan
Frank J. M. van Kuppeveld
Ron A. M. Fouchier
Adolfo Garcia-Sastre
Erik de Vries
Cornelis A. M. de Haan
Source :
mBio, Vol 12, Iss 3 (2021)
Publication Year :
2021
Publisher :
American Society for Microbiology, 2021.

Abstract

Since its emergence in 2009, the pandemic H1N1 influenza A virus (IAV) has caused significant disease and mortality in humans. IAVs contain two envelope glycoproteins, the receptor-binding hemagglutinin (HA) and the receptor-destroying neuraminidase (NA).

Subjects

Subjects :
Microbiology
QR1-502

Details

Language :
English
ISSN :
21507511
Volume :
12
Issue :
3
Database :
Directory of Open Access Journals
Journal :
mBio
Publication Type :
Academic Journal
Accession number :
edsdoj.163ddbb305ac4bb68f81dbc7e705a477
Document Type :
article
Full Text :
https://doi.org/10.1128/mBio.00287-21