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Zebrafish pigment cells develop directly from persistent highly multipotent progenitors

Authors :
Tatiana Subkhankulova
Karen Camargo Sosa
Leonid A. Uroshlev
Masataka Nikaido
Noah Shriever
Artem S. Kasianov
Xueyan Yang
Frederico S. L. M. Rodrigues
Thomas J. Carney
Gemma Bavister
Hartmut Schwetlick
Jonathan H. P. Dawes
Andrea Rocco
Vsevolod J. Makeev
Robert N. Kelsh
Source :
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Publication Year :
2023
Publisher :
Nature Portfolio, 2023.

Abstract

Neural crest cells are highly multipotent stem cells, but it remains unclear how their fate restriction to specific fates occurs. Here, the authors show in zebrafish that broad multipotency is retained even after migration, suggesting that fate restriction occurs directly, but dynamically.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
14
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.160bd44df47e4c13899e32cf8a80ef54
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-023-36876-4