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Robust detection of translocations in lymphoma FFPE samples using targeted locus capture-based sequencing
- Source :
- Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
- Publication Year :
- 2021
- Publisher :
- Nature Portfolio, 2021.
-
Abstract
- Preservation of cancer biopsies by FFPE introduces DNA fragmentation, hindering analysis of rearrangements. Here the authors introduce FFPE Targeted Locus Capture for identification of translocations in preserved samples.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Volume :
- 12
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.15e52e7d12f34aa7b62f485085760e59
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s41467-021-23695-8